Slash played guitar on two hit singles, "Black Or White" and "Give In to Me". He also appeared in the music video of the latter.
He appeared twice on stage with Jackson to perform Black or White during his Dangerous World Tour in Oviedo and Tokyo in 1992.
Slash and Jackson appeared together at the MTV Video Music Awards of 1992 and 1995.
Slash also played guitar in "D.S.", a controversial song from the HIStory album of 1995.
In 2001, Slash joined Jackson on stage at the Michael Jackson: 30th Anniversary Special playing guitar while Jackson performed his hit songs, "Black Or White" and "Beat It".